7/31/2023 0 Comments Stericycle spore testing![]() Aerosol generation procedures and those that generate splashes may also contaminate surfaces, personnel, and potentially expose workers (e.g., inhalation, contact with mucous membranes) to pathogens. In the laboratory setting, high concentrations of pathogens are commonplace, and containment of environmental surfaces (e.g., benchtops, equipment, personal protective equipment (PPE)) and hands of the laboratorian may occur. Additionally, the pathogen in question must overcome environmental stresses to retain viability (e.g., ability to form biofilms in low, nutrient-moist environments or distribution systems ability to survive dehydration), virulence, and the capability to initiate infection in the host. The absence of any one element will reduce and/or prevent the potential for transmission. To accomplish successful transmission from an environmental source, all of these requirements for the chain of infection must be present. a correct portal of entry to a susceptible host, and.a mechanism of transmission of the pathogen from environment to the host,.sufficient dose of a pathogen to cause infection (i.e., infectious dose),.the presence of a pathogen of sufficient virulence,.5,6 The requirements needed for environmental transmission include: Fortunately, LAI are relatively rare events because there are several requirements necessary for environmental transmission to occur. Laboratory-associated infections (LAIs) can be transmitted directly or indirectly from environmental sources within the laboratory (e.g., air, fomites and laboratory instruments, aerosols, and splashes) to laboratory staff. Environmentally Mediated Infection Transmission Safe use of chemicals within the laboratory falls under the OSHA Laboratory Standard. The FDA has defined three types of liquid chemical germicides for processing medical devices, and these germicides are regulated as auxiliary devices (FDA 1977 Policy Manual):ĭisinfectants used in the laboratory include those recommended by equipment manufacturers and a broad-spectrum product, typically an intermediate-level disinfectant (i.e., a product with a mycobacteriology claim). The list of selected EPA-registered disinfectants are available on the EPA website. The more commonly used public health antimicrobial products are described in the Glossary (e.g., sporicides, disinfectants, and sanitizers). ![]() 3 The laboratory is responsible for selecting an appropriate EPA-registered product and using it according to the manufacturer’s instructions on the product label. RegulationsĪntimicrobial pesticides (e.g., disinfectants) are classified as pesticides and are regulated by both the United States Environmental Protection Agency (EPA) under the authority of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1,2 and the United States Food and Drug Administration (FDA), Center for Devices and Radiologic Health by the Food Quality Protection Act (FQPA).
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